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  • Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
    Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed and potentially fatal disease of the heart muscle As it progresses, the heart can become unable to adequately squeeze to pump blood out of the heart, ultimately leading to heart failure
  • Hereditary Transthyretin-Mediated Amyloidosis (hATTR) Clinical Clues . . .
    Wild-type ATTR (wATTR) amyloidosis presents primarily with cardiac manifestations, whereas hereditary or variant ATTR (hATTR or ATTRv) amyloidosis variably involves the heart and autonomic and peripheral nerves
  • Genetic Testing and Counseling for Hereditary Transthyretin Amyloidosis . . .
    Learn about the importance of genetic testing for hATTR Amyloidosis, including who should get tested and genetic counseling
  • Dempsey’s Encouraging Words: “There’s Help Out There!”
    Some people with wild-type ATTR-CM have limited symptoms while others develop end-stage heart failure Affecting mostly men, wild-type ATTR-CM can also cause a host of seemingly unrelated conditions, such as bilateral carpal tunnel syndrome, lumbar spinal stenosis, biceps tendon rupture and neuropathy, or tingling and numbness in the extremities
  • Cardiac Amyloidosis - American Heart Association
    Grogan, M et al “Natural history of wild-type transthyretin cardiac amyloidosis and risk stratification using a novel staging system”, JACCC Volume 68, No 10, 2016 Kapoor, P, Thenappan, T, Singh, E, Kumar, S and Greipps, P “Cardiac amyloidosis: a practical approach to diagnosis and management The American Journal of Medicine 2011
  • Advancing access to clinical trials for cardiomyopathy
    As part of this work, the Association today announced an initiative to improve education, outreach and access to clinical trials for gene editing therapies for transthyretin amyloid cardiomyopathy (ATTR-CM) ATTR-CM is a progressive and often underdiagnosed condition that disproportionately affects older adults and certain racial and ethnic groups
  • Blog Article: Don Chaney: Determined to Pull Out a Win
    There are 2 sub-types of ATTR-CM: wild-type, which occurs as you age, and the hereditary form of ATTR-CM (hATTR-CM), which is caused by a gene mutation Chaney learned he is living with the hereditary sub-type There are many mutations that cause the hereditary form of ATTR-CM The most common one is found in about 1 out of every 25 African
  • Transthyretin Amyloidosis (ATTR) for Professionals
    Video webinar series helps instructs healthcare professionals in improving care and treatment for patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)





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