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  • A Sweet Combination: Developing Saccharin and Acesulfame K . . . - PubMed
    The sweeteners saccharin (SAC) and acesulfame K (ACE) recently entered the topic of anticancer human carbonic anhydrase (CA, EC 4 2 1 1) inhibitors, as they showed to selectively inhibit the tumor-associated CAs IX XII over ubiquitous CAs
  • “Seriously Sweet”: Acesulfame K Exhibits Selective Inhibition Using . . .
    Previously, saccharin, a commonly used artificial sweetener, has been observed to selectively inhibit CA IX over other CA isoforms In this study, X-ray crystallography showed acesulfame potassium (Ace K) binding directly to the catalytic zinc in CA IX (mimic) and through a bridging water in CA II
  • Fact Sheet: ACEs Aware in California
    Number of ACE screenings conducted in California between January 1, 2020, and June 30, 2023, based on DHCS Medi-Cal claims data 64% of participants indicated that based on the training, they plan to implement changes in their practice
  • Carbonic anhydrases: novel therapeutic applications for inhibitors and . . .
    Carbonic anhydrases (CAs; also known as carbonate dehydratases EC 4 2 1 1) are ubiquitous metalloenzymes present in prokaryotes and eukaryotes that are encoded by four evolutionarily unrelated
  • What Is Acesulfame Potassium (E950)? Uses, Safety, Side Effects
    Acesulfame potassium, 200 times sweeter than sugar, is an artificial sweetener used in food and beverage to replace sugar by providing a sweet taste with no calories and zero glycemic index, which may be helpful in controlling weight obesity and benefit to diabetes The European food additive number is E950
  • The ACEs Aware Initiative - California
    To incentivize early detection and early intervention for toxic stress by reimbursing providers for screening for ACEs, which includes assessing for the triad of adversity (ACE score), clinical manifestations of toxic stress (ACE-Associated Health Conditions, AAHCs), and protective factors
  • CA: A Cancer Journal for Clinicians - Wiley Online Library
    CA publishes information about the prevention, early detection, and treatment of cancer, as well as nutrition, palliative care, survivorship, and additional topics of interest related to cancer care The journal also accepts proposals for high-impact randomized trials that inform standards of care
  • Angiotensin-converting enzyme - Wikipedia
    Angiotensin-converting enzyme (EC 3 4 15 1), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II
  • Ace It! Exam Prep Course | Canadian Anesthesiologists Society - cas. ca
    Register for the Annual Meeting, and add the Ace It! A Prep Course for the Royal College Exam (Oral Exam) to your agenda at no additional cost Registration will remain open until Sunday, June 1, 2025
  • CALIFORNIA LAUNCHES “ACEs AWARE” INITIATIVE TO ADDRESS THE . . . - DHCS
    Beginning January 1, 2020, Medi-Cal providers can be paid for ACEs screenings for Medi-Cal patients Through the ACEs Aware initiative, Medi-Cal providers can receive training, clinical protocols, additional resources, and payment for screening children and adults for ACEs





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