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  • Myc - Wikipedia
    The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN) c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc
  • Nature reviews | MYC 在癌症中的作用：从难以药物靶向的目标到临床试验
    Whitfield研究员和Laura Soucek教授2025年2月19日在Nature reviews drug discovery发表了最新关于 MYC靶点 的综述，介绍了该靶点的研究进展，以及靶向MYC的药物开发策略，聚焦最新抑制剂和进入临床试验的药物，关注MYC 抑制剂的临床应用。
  • MYC Gene - GeneCards | MYC Protein | MYC Antibody
    MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene Diseases associated with MYC include Burkitt Lymphomaand High-Grade B-Cell Lymphoma Double-Hit Triple-Hit
  • MYC in cancer: from undruggable target to clinical trials
    This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials
  • The MYC oncogene — the grand orchestrator of cancer growth and immune . . .
    MYC has two paralogues: MYCL and MYCN The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small-cell lung cancer and N-MYC with neuroblastoma
  • MYC on the Path to Cancer: Cell
    Other approaches to halt Myc on the path to cancer involve targeting Myc-Max dimerization or Myc-induced microRNA expression Here the richness of our understanding of MYC is reviewed, highlighting new biological insights and opportunities for cancer therapies
  • MYC: Master Regulator of Cell Death and Tumor Progression
    MYC is a transcription factor that regulates the expression of numerous genes involved in critical cellular processes, such as metabolism, stress response, and proliferation
  • Myc - an overview | ScienceDirect Topics
    Myc family proteins (c-Myc, N-Myc, L-Myc, and B-Myc) are basic helix–loop–helix leucine zipper TFs, and their expression is tightly regulated at multiple levels, including transcription, translation, and protein stability
  • Disrupting MYC RNA Interactions Promotes Tumor Regression
    While MYC is commonly regarded as an oncoprotein that localizes to promoters and drives transcription of protumorigenic gene programs, emerging studies suggest that its role in cancer may extend beyond its DNA-binding capacity However, the mechanisms and consequences of DNA-independent MYC activity remain poorly understood Uhl, Aziba, Löbbert, and colleagues sought to address this by using





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