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  • Organoid Research - STEMCELL
    Organoids may be generated from adult stem cell-containing tissue samples, single adult stem cells, or via the directed differentiation of pluripotent stem cells 3,4 Due to the active stem cell population that are present in some organoid model systems, the organoids can be greatly expanded
  • Organoids: A new window into disease, development and . . .
    Organoids grow from stem cells—cells that can divide indefinitely and produce different types of cells as part of their progeny Scientists have learned how to create the right environment for the stem cells so they can follow their own genetic instructions to self-organize, forming tiny structures that resemble miniature organs composed of
  • Human organoids: model systems for human biology and medicine
    One feature that is common to all organoids is that they are generated from pluripotent stem cells (PSCs) or adult stem cells (AdSCs; also known as tissue stem cells) by mimicking human
  • Organoids: The current status and biomedical applications
    Organoids can be defined as cells with stem cell potential that are incubated under 3D culture systems to aggregate by adhesion, self‐organize, and differentiate into 3D cell masses with the corresponding organ tissue morphology 27 Organoids have a high degree of similarity to their parental cells that replicate and simulate their unique
  • Organoids: Modeling Development and the Stem Cell Niche in a . . .
    Lastly, collaborations between bioengineers and stem cell biologists can foster fundamental biological studies on the regulatory role of the composition and rigidity of the ECM, in which organoids are cultured, for stem cell self-renewal and differentiation, as highlighted by a recent report (Cassereau et al , 2015), or devise strategies to





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