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  • Liverpool COVID-19 Interactions
    Comprehensive, up-to-date, evidence-based COVID19 drug-drug interaction resource, freely available to healthcare workers, patients and researchers
  • IDSA Guidelines on the Treatment and Management of Patients with COVID-19
    Pharmacologic Treatment of Severe COVID-19 Patients with severe COVID-19 are those whose infection has pulmonary involvement resulting in hypoxia while breathing room air and or needing treatment with low flow oxygen
  • Managing Drug Interactions When Treating Patients for COVID-19
    Describe risk factors for clinically relevant drug-drug interactions while on oral antivirals to treat COVID-19 List the major types of drug-drug interactions between oral antivirals, ritonavir-boosted nirmatrelvir (Paxlovid) and molnupiravir, and select classes of medications
  • COVID-19 Treatment Clinical Care for Outpatients - CDC
    Pre-exposure prophylaxis (prevention) medication is available for some people who are moderately or severely immunocompromised for additional protection against COVID-19 Patients who are at higher risk for severe COVID-19 might benefit from outpatient treatment
  • Detecting drug-drug interactions between therapies for COVID-19 and . . .
    We conducted a discovery-driven data analysis to identify potential DDIs and associated adverse events (AEs) in COVID-19 patients from the FDA Adverse Event Reporting System (FAERS), a source of post-market drug safety Materials and Methods: We investigated 18,589 COVID-19 AEs reported in the FAERS database between 2020 and 2021
  • Recommendations for Drug Therapy for Adults with Severe to Critical . . .
    Patients must have COVID-19 symptoms and a positive test based on polymerase chain reaction (PCR), rapid molecular or rapid antigen test to be eligible for COVID-19 drug therapy Dexamethasone is recommended for all patients with severe or critical COVID-19 Remdesivir is recommended for all patients with severe COVID-19
  • COVID-19 Drug Interactions - jcritintensivecare. org
    Elderly patients are at high risk of corona virus disease 2019 (COVID-2019) infection and severe COVID-19 patients are treated in intensive care units (ICU) Drug-drug interaction risk increased to 100% with eight or more medication use
  • Adverse drug reactions and drug interactions in the treatment of . . .
    Therapies considered off label for treating COVID-19 include the following drugs: hydroxychloroquine sulfate, azithromycin, tocilizumab, lopinavir ritonavir, and interferon The use of antibacterial agents for pneumonia treatment was considered a supplemental therapy
  • Recommendations for the Management of Drug–Drug Interactions Between . . .
    Options for mitigating risk from DDIs with nirmatrelvir ritonavir are limited due to the clinical illness, the short window for intervention, and the related difficulty of implementing clinical monitoring or dosage adjustment of the comedication
  • Drug-Drug Interactions With Nirmatrelvir Ritonavir (Paxlovid) and . . .
    with nirmatrelvir ritonavir and seeking alternative treatment options for COVID-19 may be prudent Conversely, if the risk of severe COVID-19 is high and interrupting a cardiovascular medication is less likely to cause harm — for instance, temporarily stopping atorvastatin in a patient with chronic coronary artery d





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