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  • NoRC associated RNA - Wikipedia
    NoRC associated RNA (also known as pRNA) is a non-coding RNA element which regulates ribosomal RNA transcription by interacting with TIP5, part of the NoRC chromatin remodeling complex Ribosomal RNA genes (rDNA) encodes for ribosomal RNA (rRNA) that constitutes the majority of the ribosome
  • pRNA: NoRC-associated RNA of rRNA operons - PMC
    Promoter-associated RNAs (pRNAs) are a family of ~90–100 nt-long divergent RNAs overlapping the promoter of the rRNA (rDNA) operon pRNA transcripts interact with TIP5, a component of the chromatin remodeling complex NoRC, which recruits enzymes for
  • Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and . . .
    RNA nanotechnology is a term that refers to the design, fabrication and use of nanoparticles that are mainly composed of RNAs via bottom-up self-assembly The packaging RNA (pRNA) of the
  • pRNA: NoRC-associated RNA of rRNA operons - PubMed
    Promoter-associated RNAs (pRNAs) are a family of ~90-100 nt-long divergent RNAs overlapping the promoter of the rRNA (rDNA) operon pRNA transcripts interact with TIP5, a component of the chromatin remodeling complex NoRC, which recruits enzymes for heterochromatin formation and mediates silencing o …
  • A pRNA‐induced structural rearrangement triggers . . . - The EMBO Journal
    We show that dissociation of 6S‐1 RNA:RNAP complexes is the result of a structural rearrangement of 6S‐1 RNA induced by pRNA transcripts that have a minimal length (⩾12nt) to confer sufficient stability to pRNA:6S‐1 RNA hybrid duplexes
  • Full article: pRNA - Taylor Francis Online
    Promoter-associated RNAs (pRNAs) are a family of ~90–100 nt-long divergent RNAs overlapping the promoter of the rRNA (rDNA) operon pRNA transcripts interact with TIP5, a component of the chromatin remodeling complex NoRC, which recruits enzymes for heterochromatin formation and mediates silencing of rRNA genes
  • The structure of NoRC-associated RNA is crucial for targeting the . . .
    Silencing of ribosomal RNA genes (rDNA) requires binding of the chromatin remodelling complex NoRC to RNA that is complementary to the rDNA promoter NoRC-associated RNA (pRNA) folds into a conserved stem–loop structure that is required for nucleolar localization and rDNA silencing





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