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lactam

乳胺; 内酰胺

乳胺; 内□胺

The Collaborative International Dictionary of English v.0.48 (gcide)

Lactam \Lac"tam\, n. [Lactone amido.] (Chem.)
One of a series of anhydrides of an amido type, analogous to
the lactones, as oxindol; a cyclic amide.
[1913 Webster]

{beta-lactam} or {[beta]-lactam},
(a) a lactam in which the amide bond is contained within a
four-membered ring, which includes the amide nitrogen and
the carbonyl carbon.
(b) an antibiotic containing a beta-lactam, such as a
{penicillin}, {cephalosporin}, or {carbapenem}; also
called a {beta-lactam antibiotic}. [informal, laboratory
slang]
[PJC]

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英文字典中文字典相关资料:

Lactam - Wikipedia
A lactam is a cyclic amide, formally derived from an amino carboxylic acid through cyclization reactions [1] The term is a portmanteau of the words lactone + amide
β-Lactam - Wikipedia
The β-lactam ring is part of the core structure of several antibiotic families, the principal ones being the penicillins, cephalosporins, carbapenems, and monobactams, which are, therefore, also called β-lactam antibiotics
Lactam - an overview | ScienceDirect Topics
Lactam groups contained in quinolizidine systems exhibit the expected reactivity This behavior is exemplified by the nucleophilic addition of organomagnesium reagents, which, when combined with a reduction step, can be used to obtain alkyl derivatives in a one-pot sequence
LACTAM Definition Meaning | Merriam-Webster Medical
The meaning of LACTAM is any of a class of amides of amino carboxylic acids that are formed by the loss of a molecule of water from the amino and carboxyl groups, that are characterized by the carbonyl-imido group —CONH— in a ring, and that include many antibiotics
Lactame – Wikipedia
Lactame (Singular: das Lactam; Synonym: intramolekulares Amid, Kunstwort aus Lacton und Amid) nennt man cyclische organisch-chemische Verbindungen, die eine Amid-Bindung im Ring enthalten
β-Lactam antibiotic targets and resistance mechanisms: from covalent . . .
In this review, we discuss the competing processes of β-lactam antibiotic development and bacterial resistance We begin by providing an overview of the major subclasses of β-lactam antibiotics, and then describe their activities as covalent inhibitors of PBPs
Overview of Beta-Lactams - Infectious Disease - Merck Manual . . .
Beta-lactamases are a diverse class of enzymes produced by bacteria that break open the beta-lactam ring, inactivating the beta-lactam antibiotic Some beta-lactamases are encoded on mobile genetic elements (eg, plasmids); others are encoded on chromosomes
Lactam - an overview | ScienceDirect Topics
The β-lactam antibiotics is a family of bactericidal drugs structurally-related containing the β-lactam ring in their chemical structure They are classified in penicillins, cephalosporins, carbapenems, penems (also known as thiopenems) and monobactams
21. 11: Chemistry Matters—β-Lactam Antibiotics
Lactam antibiotics are essential in modern medicine Lactams, particularly β-lactams like penicillin and cephalosporins, inhibit bacterial cell wall synthesis by targeting peptidoglycan

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