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  • Ketamine - Wikipedia
    Ketamine is a cyclohexanone -derived dissociative general anesthetic and NMDA receptor antagonist with analgesic and hallucinogenic properties, used medically for anesthesia, depression, and pain management [20][21] Ketamine exists as its two enantiomers, S - (esketamine) and R - (arketamine), and has antidepressant action likely involving
  • Ketamine: Uses, Dosage, Side Effects, Warnings - Drugs. com
    Ketamine is used as an anesthetic for surgery, a treatment for depression (off-label), and is a drug of abuse Includes ketamine side effects, interactions and indication
  • Ketamine Therapy: What It Is, How It Works Side Effects
    Ketamine therapy uses a medicine called ketamine hydrochloride to manage certain mental health conditions and chronic pain Ketamine is a fast-acting anesthetic It can make you feel relaxed or slightly detached from your surroundings for a short time
  • What Is Ketamine? How It Works and May Help With Severe Depression - WebMD
    Is ketamine a treatment for depression? What are the risks? Learn about the uses, benefits, and side effects of ketamine
  • The Bright and Dark Sides of Ketamine - Psychology Today
    Ketamine The Bright and Dark Sides of Ketamine Off-label unsupervised use of ketamine is a risk to many besides Matthew Perry Updated March 18, 2026 | Reviewed by Hara Estroff Marano
  • Ketamine | Definition, Uses, Facts | Britannica
    Ketamine is a general anesthetic agent related structurally to the hallucinogen phencyclidine (PCP) Ketamine was first synthesized in 1962 by an American scientist who was searching for a new anesthetic to replace PCP, which was not suitable for use in humans because of the severe hallucinogenic effects it produced
  • Ketamine: What Is It, uses, treatments, effects, and more effects
    Ketamine is an anesthetic used to induce a loss of consciousness and relieve pain Read about its medical and recreational uses, and the risks involved
  • Ketamine - DEA. gov
    Ketamine has also been used to facilitate sexual assault Ketamine is an approved medical product as an injectable, short-acting anesthetic for use in humans and animals and as esketamine (Spravato®; the active form of the drug) as a nasal spray for treatment resistant depression
  • Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular . . .
    Ketamine is a hydrosoluble aryl‐cyclo‐alkylamine (Figure 1) with a molecular mass of 238 g mol and a pKa 7 5 Used as a chlorhydrate in a slightly acid (pH 3 5–5 5) aqueous solution, ketamine sometimes includes benzethonium chloride or chlorobutanol as preservatives The second carbon of the cyclohexanone radical is asymmetrical
  • Ketamine—From an Anesthetic to a Psychiatric Drug: Mechanisms of Action . . .
    Ketamine, originally developed as an anesthetic, is gaining increasing attention due to its multifaceted pharmacological properties In addition to its use in anesthesia, ketamine exerts potent analgesic effects via N-methyl-D-aspartate (NMDA)





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