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  • Neuromuscular Home Page
    Fellowships Neuromuscular Medicine Pathology Neuromuscular Lab Requisitions Antibody Biopsy Make a Gift
  • Polyneuropathy Differential Diagnosis
    Index Search Myopathy Neuropathy Synapse CNS Lab tests Basic Subcellular Washington University Go to Differential Diagnosis of Myopathies Return to Neuromuscular Home Page or newly revised Other revisions 11 18 2025
  • Myopathy Differential Diagnosis
    See Neuromuscular Syndromes Go to Differential Diagnosis of Neuropathies Return to Neuromuscular Home Page or newly revised Other revisions 2 14 2024
  • NEUROMUSCULAR PERSONNEL
    The Neuromuscular Clinical Laboratory provides Antibody testing Antibodies tested Test request form Neuromuscular pathology (Muscle Nerve biopsies) We evaluate more than 600 muscle 100 nerve biopsies each year
  • Neuromuscular Clinical Laboratory
    Most common preparation Useful for: Inflammatory cells Deficiencies: Fine structure; Myelin pathology; Axon loss Ultrastructure: When necessary Requisition form: Printable PDF Nerve biopsies: Information Certification: Alan Pestronk MD Neuromuscular Pathology Training Program
  • Serum Requisition - Washington University in St. Louis
    Additional antibodies include IgM binding to histone H3 and or GD1a ganglioside and IgG binding to sulfatide and or GM1 ganglioside The values of the additional antibody titers are listedon the report Interpretations are provided for all antibody tests Street address: Neuromuscular Laboratory, 509 South Euclid, Room 404, St Louis, MO 63110
  • Motor Syndromes - Washington University in St. Louis
    Paraneoplastic Lower Motor Neuron Syndrome 8, 25 Epidemiology: Single patient, 72 year old female Onset: 4 months before diagnosis of tumor Clinical Weakness Asymmetric at onset Arms Legs Severe Lower motor neuron only Bulbar: Hypophonia; Dysphagia; Unilateral facial paresis Painless Course Progressive over months Improvement after tumor removal Long-term residual disability Sensation
  • NEUROMUSCULAR DISEASE: TYPICAL PATTERNS
    General: The neuromuscular evaluation Begins with: Evaluation description of patterns of disease process Gleaned from: History physical examination Unusual patterns Especially important Provide basis for listing most likely diagnoses Summary of disease syndrome should include features from each descriptive category Function: Motor; Sensory
  • Neuromuscular: Fiber Activity
    Neuromuscular Muscle stiffness Myotonia: Onset after birth Face: Fixed expression, Pursed lips, Small mouth Thighs Waddling gait Crouched stance Treatment: Carbamazepine Muscle hypertrophy: Especially thighs; Generalized Malignant Hyperthermia: Increased risk during anesthesia Tendon reflexes: Reduced Mental retardation: Mild; Rare Skeletal
  • NEUROMUSCULAR CLINICAL LABORATORY
    NEUROMUSCULAR CLINICAL LABORATORY: Antibody Information To obtain antibody testing: · Draw blood in a red top tube · Send: 2 to 3 ml of serum · Send with requisition, at room temp (freezing is not necessary), via overnight mail to Neuromuscular Clinical Lab: Pestronk Washington University Medical School Department of Neurology, Box 8111





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