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  • Modelling the cardiovascular effects of ephedrine - PMC
    Why systolic blood pressure demonstrates tolerance to ephedrine, but heart rate effects do not, is unknown However this difference may be explained by differential desensitization between β 1 and β 2 receptors or between various tissues expressing these receptors As mentioned, clockwise hysteresis is indicative of pharmacodynamic tolerance
  • Three Factors That Could Be Impacting Your ECG Interpretation
    While filtering can yield a clean-looking ECG, too much filtering can distort or remove authentic waveform data The problem with overly filtered ECGs is that you may not know what you’re missing Physicians need to be aware of the filtering that takes place on any given ECG, and its potential impact on the interpretation
  • The Impact Of Cardiovascular Pharmacology On ECG Changes
    Common ECG Changes Associated With Specific Medications Cardiovascular drugs affect heart rate, heart rhythm, blood pressure, and the force of heart muscle contractions Because of these effects, they can cause noticeable changes in ECG readings The following table summarizes some of the most common medications and their ECG impact:
  • Direct and Indirect Effects of Ephedrine on the . . .
    Sympathectomy did not significantly affect cardiac or depressor responses to the direct beta-adrenoceptor agonist isoprenaline Sympathectomy significantly reduced the tachycardia to (±)-ephedrine It is concluded, firstly, that (−)-ephedrine is more potent than the racemate mixture at producing pressor responses
  • Cardiovascular effects of ephedrine during cardiopulmonary . . .
    Although ephedrine was first isolated by Nagai in 1887, the mechanisms of its action on the cardiovascular system are not entirely clear Based on recent literature data, the cardiovascular effects of ephedrine are mainly mediated indirectly through endogenous norepinephrine (NE) release from adrenergic terminals, especially from a cytoplasmic pool, as well as by preventing catecholamine
  • Effect of 25 mg kg ephedrine ϩ 30 mg kg caffeine on ECG in a . . .
    Download scientific diagram | Effect of 25 mg kg ephedrine ϩ 30 mg kg caffeine on ECG in a 14-wk old rat Abnormal ECG is from an animal that died showing reduced R-wave amplitude An example of
  • Modelling the cardiovascular effects of ephedrine - PubMed
    Plasma ephedrine concentrations, heart rate and blood pressure were determined for 8 h postdose Results: The pharmacokinetics of ephedrine were best described by a one-compartment model with first-order absorption and elimination The percentage change in heart rate was described by a linear model with a resulting slope of 0 14% l microg(-1





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