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openhearted    
a. 坦率的,直率的

坦率的,直率的

openhearted
adj 1: showing or motivated by sympathy and understanding and
generosity; "was charitable in his opinions of others";
"kindly criticism"; "a kindly act"; "sympathetic words";
"a large-hearted mentor" [synonym: {charitable},
{benevolent}, {kindly}, {sympathetic}, {good-hearted},
{openhearted}, {large-hearted}]
2: freely communicative; candidly straightforward; "openhearted
advice"

Open-hearted \O"pen-heart`ed\, a.
Candid; frank; generous. --Dryden. -- {O"pen-heart`ed*ly},
adv. -- {O"pen-heart`ed*ness}, n. --Walton.
[1913 Webster]

93 Moby Thesaurus words for "openhearted":
amiable, artless, bighearted, bluff, blunt, born yesterday,
bounteous, bountiful, broad, brusque, candid, childlike, confiding,
cordial, direct, downright, explicit, forthright, frank,
frankhearted, free, free-speaking, free-spoken, free-tongued,
freehanded, freehearted, friendly, generous, genial, genuine,
giving, gracious, greathearted, guileless, handsome,
heart-to-heart, hearty, hospitable, ingenu, ingenuous, innocent,
large, largehearted, lavish, liberal, magnanimous, munificent,
naive, neighborly, open, openhanded, outspoken, plain,
plain-spoken, princely, profuse, receptive, round, simple,
simplehearted, simpleminded, sincere, single-hearted,
single-minded, stintless, straight, straight-out, straightforward,
transparent, trustful, trusting, unchecked, unconcealed,
unconstrained, undisguised, undissembled, undissembling,
unequivocal, ungrudging, unguarded, unreserved, unrestrained,
unselfish, unsophisticated, unsparing, unstinted, unstinting,
unsuspicious, unvarnished, unwary, warm, warmhearted, welcoming


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  • npgrj_nprot_320 2583. . 2589 - Luo Lab
    Mosaic analysis with a repressible cell marker (MARCM) is a genetic technique used in Drosophila to label single cells or multiple cells sharing a single progenitor Labeled homozygous mutant cells can be generated in an otherwise unlabeled heterozygous animal Mutant or wild-type labeled cells can also be made to express one or more transgenes
  • Bloomington Drosophila Stock Center: Indiana University Bloomington
    Mosaic Analysis with a Repressible Cell Marker (MARCM) is a FLP FRT-based genetic mosaic system to label either neurons derived from a common progenitor or isolated single neurons
  • A protocol for mosaic analysis with a repressible cell marker (MARCM . . .
    Mosaic analysis with a repressible cell marker (MARCM) is a genetic technique used in Drosophila to label single cells or multiple cells sharing a single progenitor
  • Microsoft Word - Luo. doc
    In many cases, it is desirable to visualize the mutant cells but not heterozygous parents or homozygous wild type siblings The MARCM (for Mosaic Analysis with a Repressible Cell Marker) system we developed (Lee and Luo, 1999) serves this purpose
  • Overview of MARCM-Related Technologies in Drosophila . . . - PubMed
    Mosaic analysis with a repressible cell marker (MARCM)-related technologies are positive genetic mosaic labeling systems that have been widely applied in studies of Drosophila brain development and neural circuit formation to identify diverse neuronal types, reconstruct neural lineages, and investig …
  • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila . . .
    The MARCM system can be used for cell lineage analysis by taking advantage of the following properties First, one can use heat shock to induce FLP expression at a specific stage, and only precursors that divide actively at that stage are subject to mitotic recombination
  • Overview of MARCM-Related Technologies in . . . - Current Protocols
    Mosaic analysis with a repressible cell marker (MARCM)–related technologies are positive genetic mosaic labeling systems that have been widely applied in studies of Drosophila brain development and n
  • Mosaic analysis with a repressible cell marker (MARCM) for . . .
    The MARCM system can be used for cell lineage analysis by taking advantage of the following properties First, one can use heat shock to induce FLPexpression at a specific stage, and only precursors that divide actively at that stage are subject to mitotic recombination
  • Tool Development - Luo Lab
    For example, the MARCM (mosaic analysis with a repressible cell marker) method in flies and MADM (mosaic analysis with double markers) method in mice allow the visualization and genetic manipulation of isolated single neurons (see Figs 1-1, 2-1, 2-2, 3-1)
  • The Q System: A Repressible Binary System for Transgene Expression . . .
    The Q system-based MARCM (Q-MARCM) can then be used to mark and genetically manipulate a single cell or a small pop-ulation of cells, while GAL4 UAS can be used to genetically manipulate a separate population of cells in the same animal
  • doi:10. 1016 j. brainresrev. 2007. 01. 012 - luolab. stanford. edu
    MARCM stands for Mosaic Analysis with a Repressible Cell Marker (Lee and Luo, 1999) The essence of MARCM is to couple cell division with the loss of a transcriptional repressor (Gal80) in one of the two daughter cells, thus allowing (Gal4 UAS driven) marker expression in one, but not the other, daughter cell, nor in any parental cells (Fig 1A)
  • 以MARCM标记单细胞在果蝇神经系统的应用 —BIO-101
    摘要： 在以果蝇为实验材料的研究中，常利用Mosaic analysis with a repressible maker (MARCM) 标记单个或一群细胞，以观察神经细胞的形态 (morphology) 或操控基因的表达。 MARCM的作用原理是当母细胞 (parental cell) 的同源染色体经由 FRT 发生染色体重组 (homologous chromosome recombination)，经细胞分裂后即有机会产生一个不带有GAL80的子细胞，而使得GAL4得以作用。 因为这项技术可标记特定细胞谱系中的单个或一小群细胞，因此适合用于研究细胞谱系、神经回路以及探讨特定基因在神经细胞或其他组织中的功能。
  • npgrj_nprot_320 2583. - Nature
    Mosaic analysis with a repressible cell marker (MARCM) is a genetic technique used in Drosophila to label single cells or multiple cells sharing a single progenitor Labeled homozygous mutant
  • 以MARCM 标记单细 - Bio-protocol
    胞的形态 (morphology) 或操控基因的表达。MARCM的作用原理是当母细胞 (parental cell) 的同源染色体经由FRT发生染色体重组 (homologous chromosome recombination),经细胞分裂后即有机会产生一个� 带有GAL80 的子细胞,而使得GAL4得以作用。因为这项技术可标记特定细胞谱系中的单个或一小群细胞,因此适合用于研究细胞谱系、神经回路以及探讨�
  • MA in Public Policy with Certificate in Research Methods
    MACRM is a two-year program that is part public policy degree, part research apprenticeship, and part intensive research methods training It’s designed to be a stepping stone to either a PhD or serious quantitative research jobs in academia, think tanks, and policy organizations





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