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  • Smallpox - World Health Organization (WHO)
    Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family It was one of the most devastating diseases known to humanity and caused millions of deaths before it was eradicated It is believed to have existed for at least 3000 years The smallpox vaccine, created by Edward Jenner in 1796, was the first successful vaccine to be developed He
  • Smallpox - World Health Organization (WHO)
    Smallpox is an ancient disease caused by the variola virus Early symptoms include high fever and fatigue The virus then produces a characteristic rash, particularly on the face, arms and legs The resulting spots become filled with clear fluid and later, pus, and then form a crust, which eventually dries up and falls off Smallpox was fatal in up to 30% of cases Smallpox has existed for at
  • Smallpox - World Health Organization (WHO)
    Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family It was one of the most devastating diseases known to humanity and caused millions of deaths before it was eradicated It is believed to have existed for at least 3000 years The smallpox vaccine, created by Edward Jenner in 1796, was the first successful vaccine to be developed He
  • Research using live variola virus - World Health Organization (WHO)
    The period since the eradication of smallpox has been defined by a continuing debate on the destruction of the last remaining stocks of live variola virus vs their retention for ongoing research for the benefit of humanity Variola virus remaining in two high security laboratories consists of isolates of variola major and of the milder form, variola minor The two repositories and research
  • WHO Advisory Committee on Variola Virus Research
    The Advisory Committee for Variola virus Research (ACVVR) was convened in 1999 to implement WHA Resolution (WHA52) The ACVVR is composed of members from all WHO regions and advised by scientific academic experts from areas such as public health, fundamental applied research and regulatory agencies
  • Smallpox: Clinical diagnosis - World Health Organization (WHO)
    Publications of the World Health Organization Overview Smallpox has two main forms: variola major and variola minor The two forms showed similar lesions The disease followed a milder course in variola minor, which had a case fatality rate of less than 1 per cent The fatality rate of variola major was around 30% There are two rare forms of smallpox: haemorrhagic and malignant In the former
  • Smallpox - World Health Organization (WHO)
    Smallpox is an acute contagious disease caused by variola virus, a member of the Orthopoxvirus family Smallpox, which is believed to have originated over 3,000 years ago in India or Egypt, was one of the most devastating diseases known to humanity
  • WHO Advisory Committee on Variola Virus Research: report of the 23rd . . .
    The World Health Organization (WHO) Advisory Committee on Variola Virus Research (ACVVR, hereafter referred to as the Committee) held its twenty-third meeting on 3–4 November 2021 by video conference The recommendations of the Committee are summarized in the report
  • Smallpox and mpox - World Health Organization (WHO)
    Smallpox is an infectious disease caused by the variola virus of the Orthopoxvirus genus The last known naturally transmitted case occurred in Somalia in 1977, and in 1980 WHO declared smallpox eradicated Mpox is an infectious disease caused by the monkeypox virus (MPXV) of the Orthopoxvirus genus On 14 August 2024, the WHO Director-General declared the upsurge of mpox in the Democratic
  • WHO Recommendations concerning the distribution, handling and synthesis . . .
    WHO recommendations concerning the distribution, handling and synthesis of variola virus DNA, May 2008 = Recommandations de l'OMS relatives à la distribution, à la manipulation et à la synthèse de l'ADN du virus variolique, mai 20081 Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 83 (‎44)‎, 393 - 395





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